Spatial transcriptomics, or spatially resolved transcriptomics, is a method that captures positional context of transcriptional activity within intact tissue. [1]

Spatial transcriptomics (ST) is used to explore the spatial gene expression patterns of cells or tissues. It combines traditional histological techniques with high-throughput RNA sequencing to visualize and …

Jan 6, 2021 · Spatial single-cell transcriptomics is the next wave after single-cell analysis and, he says, will be particularly useful to labs studying human disease, which often starts with single cells...

Jun 27, 2022 · Since spatial information is preserved by studying intact tissue, these methods have been referred to as spatially-resolved transcriptomics, or simply ‘spatial transcriptomics’.

Jun 1, 2024 · In this review, we present the fundamental principles of spatial transcriptomic methods, discuss the challenges in data analysis, provide insights into experimental considerations, offer …

The key difference between imaging-based and sequencing-based spatial transcriptomics technologies lies in their distinct approaches to determine the spatial localization and abundance of specific mRNA …

Explore Spatial Biology and Spatial Transcriptomics with our Visium and Xenium technologies, mapping cell relationships and locations in tissue for in-depth insights.

Now, thanks to an innovative technology known as spatial transcriptomics, Mayo Clinic experts are able to examine how genes are expressed in a tissue sample in three dimensions, providing …

Jul 30, 2025 · Spatial transcriptomics works by capturing RNA molecules from a tissue section and assigning them precise spatial coordinates. This creates a detailed map of gene expression across …

Jun 26, 2025 · Spatial transcriptomics (ST) technologies have significantly advanced our capacity to quantify gene expression within tissue sections while preserving crucial spatial context information. …