The mTOR pathway is a central regulator of mammalian metabolism and physiology, with important roles in the function of tissues including liver, muscle, white and brown adipose tissue, [31] and the …

In this review, we provide an overview of our current understanding of the mTOR pathway and its role in growth, metabolism, and disease.

Oct 2, 2023 · The mammalian target of rapamycin (mTOR) is a protein kinase that controls cellular metabolism, catabolism, immune responses, autophagy, survival, proliferation, and migration, to …

Aug 5, 2025 · By integrating various signals, mTOR helps maintain cellular balance, ensuring cells respond appropriately to available resources and conditions. mTOR is not a single protein but the …

5 days ago · Discover the mTOR pathway and its role in cellular growth and metabolism. Click here to explore the intricacies of this vital signaling pathway.

The MTOR gene provides instructions for making a protein called mTOR. Learn about this gene and related health conditions.

Feb 12, 2026 · Emerging evidence reveals that the phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling pathway acts as a pivotal regulator of ABC transporters, …

2 days ago · mTOR and rapamycin are at the center of longevity research. Here’s what robust mouse studies, early human trials, and traditional practices suggest—along with the key risks and why …

Jun 2, 2024 · The mammalian target of rapamycin (mTOR) is a pivotal regulator, integrating diverse environmental signals to control fundamental cellular functions, such as protein synthesis, cell …

Many aspects of mTOR function and regulation have only recently been elucidated, and many more questions remain unanswered. In this review, we provide an overview of our current understanding of …