Cystic fibrosis transmembrane conductance regulator - Wikipedia
Cystic fibrosis transmembrane conductance regulator (CFTR) is a membrane protein and anion channel in vertebrates that is encoded by the CFTR gene. [5][6] Geneticist Lap-Chee Tsui and his team …
CFTR - Johns Hopkins Cystic Fibrosis Center
Since the discovery of the CFTR gene in 1989, more than 2,500 mutations have been identified. Cystic fibrosis is caused by mutations in the CFTR gene, which encodes a chloride channel located on the …
Basics of the CFTR Protein - Cystic Fibrosis Foundation
The CFTR protein is a particular type of protein called an ion channel. In the lung, the CFTR ion channel moves chloride ions from inside the cell to outside the cell.
CFTR: What it is and how it relates to cystic fibrosis
Sep 16, 2024 · The cystic fibrosis transmembrane conductance regulator (CFTR) is a complex protein that helps maintain fluid balance in several organs. Mutations in the CFTR protein can lead to …
CFTR gene: MedlinePlus Genetics
The CFTR gene provides instructions for making a protein called the CF transmembrane conductance regulator (CFTR). This protein functions as a channel across the membrane of cells that produce …
CFTR Gene - GeneCards | CFTR Protein | CFTR Antibody
Nov 13, 2025 · Complete information for CFTR gene (Protein Coding), CF Transmembrane Conductance Regulator, including: function, proteins, disorders, pathways, orthologs, and expression.
CFTR function, pathology and pharmacology at single-molecule
Mar 22, 2023 · The cystic fibrosis transmembrane conductance regulator (CFTR) is an anion channel that regulates salt and fluid homeostasis across epithelial membranes1.
Functional Consequences of CFTR Interactions in Cystic Fibrosis
In this review, we will provide an overview of CF disease, leading to the discovery and characterization of CFTR and the development of CFTR modulators.
What Is a CFTR Mutation and How Does It Affect the Body?
Jul 31, 2025 · The CFTR protein functions as a channel on the surface of cells that produce various fluids, including mucus, sweat, saliva, tears, and digestive enzymes. Its primary role involves …
CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; CFTR …
To avoid confusion with the previously named CF antigen (123885), Riordan et al. (1989) referred to the protein as cystic fibrosis transmembrane conductance regulator (CFTR).