Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder ...

A new method enables engineered immune progenitor cells to replace microglia in mice and reveals how a genetic mutation can lead to inflammation in the brain.

The kick-off signal for puberty begins in the brain. Specifically, in the hypothalamus, where specific neurons release a ...

Far from a static barrier, the brain’s extensive interface with the blood is increasingly being appreciated as an active border, one that serves not only to keep some proteins out, but to let others ...

Microglia are a specialized type of immune cell that accounts for about 10% of all cells within the brain and spinal cord. They function by eliminating infectious microbes, dead cells, and aggregated ...

Inflammation is triggered by the immune system and is part of the body’s natural response to injuries or disease. However, abnormal inflammation has recently been established as a hallmark for ...

Alzheimer's disease (AD) is a debilitating neurodegenerative disorder that causes progressive memory loss and a decline in mental (i.e., cognitive) abilities. Statistics suggest that between 500,000 ...

Microglia (immune cells) and the RANK protein are essential for triggering puberty and maintaining fertility in the brain.

Researchers found microglia influence reproductive hormone signaling through the RANK protein. The discovery links immune cells to puberty control and infertility, and may improve diagnosis and ...