Background. Daily suppressive therapy with valacyclovir reduces risk of sexual transmission of herpes simplex virus type 2 (HSV-2) in HSV-2–serodiscordant heterosexual couples by 48%. Whether ...
Epidemiological studies suggest that HSV-2 increases the risk of HIV-1 acquisition. 1, 2, 3 In populations with HSV-2 prevalence of 80%, nearly 50% of HIV-1 infections are attributable to an HSV-2 ...