DNA is admired for its perfection as a programmable information molecule: it uses repeating polymerization chemistry to link four nucleotide building blocks (adenine, cytosine, guanine, and thymine) ...
The other known alternate sense codon use among yeast was first identified in Candida albicans two decades ago. This too involves a CUG codon, but results in serine in the translated protein. “For ...
Features of the Formate Dehydrogenase mRNA Necessary for Decoding of the UGA Codon as Selenocysteine
The fdhF gene encoding the 80-kDa selenopolypeptide subunit of formate dehydrogenase H from Escherichia coli contains an in-frame TGA codon at amino acid position 140, which encodes selenocysteine. We ...
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