Ribozymes exist in nature as catalytic RNA molecules that either aid the hydrolysis of their own phosphodiester bonds or cause the hydrolysis of bonds in other RNAs. They also catalyze the ...

What makes ribozymes particularly interesting is that they are amenable to tinkering. Creation of a protein enzyme de novo, or modification of an existing one to function in a different way, is a ...

In new research published in the journal Angewandte Chemie, scientists applied a high throughput methodology to study the ribozyme in an innovative way. While work in this area has typically used ...

RNA molecules are an integral part of the human body: In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, allowing chemical ...

Important progress for RNA research: A team has discovered a new ribozyme that can label RNA molecules in living cells. RNA molecules are real all-rounders. They transfer the genetic information from ...

The discovery in the early 1980s that certain RNAs can behave as enzymes that catalyze RNA cleavage and ligation reactions has had a large effect on both basic and applied research. Catalytic RNAs, or ...

To understand evolution, it is important to have a comprehensive understanding of the possible catalytic roles RNA can play, roles that have been largely taken over by proteins. Only 11 classes of ...

A new method can test the activity of thousands of RNA enzymes, called ribozymes, in a single experiment. The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA ...

The "RNA world" hypothesis proposes that the earliest life on Earth may have been based on RNA - a single-stranded molecule similar in many ways to DNA - like some modern viruses. This is because, ...

The role of RNA in information transfer and catalysis highlights its dual functionalities. Our laboratory has a long-standing interest in RNA folding, recognition, and catalysis. We are especially ...

This story is part of a larger series on viroids and virusoids, small infectious RNAs. You may read the others on Forbes or www.williamhaseltine.com. Transcriptomics refers to the analysis of all the ...

RNA molecules are real all-rounders. They transfer the genetic information from the DNA in the cell. They regulate the activity of genes. And some of them have a catalytic effect: just like enzymes, ...