Sites of O-glycosylation on the spike protein were near N-glycosites, suggesting O-glycans complement N-glycans' effect in immune shielding. The severe acute respiratory syndrome coronavirus 2 ...

Text mining and knowledge graphs connect cell-culture parameters to glycosylation for faster bioprocess optimization.

Carbohydrate chemists and biochemists tend to be controlling personalities. They aren't satisfied with the way sugar groups are attached naturally to glycosylated proteins and natural products. These ...

Glycosylation is one of the most abundant of all protein post-translational modifications (PTMs). It results from the addition of sugar residues to protein sidechains to form a glycoprotein. Mammalian ...

An international team of researchers has found that glycosylation patterns are conserved across the native spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent ...

A recent study published in Engineering introduces GlycoPro, a novel high-throughput sample-processing platform that aims to transform the field of multi-glycosylation-omics analysis. Glycosylation, a ...

Glycosylation has been studied in terms of how it impacts cancer development and, more recently, neurodegeneration. One type of glycosylation is O-glycosylation, where sugars attach to oxygen atoms on ...

Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection. They are attached to many proteins in the body, ...

Association between elevated blood pressure and clinical response in patients treated with anti-vascular endothelial growth factor (anti-VEGF) therapy in phase I clinical trials. This is an ASCO ...

Plant pathogenic fungi deploy secreted effectors to suppress plant immunity responses. These effectors operate either in the apoplast or within host cells, so they are putatively glycosylated, but the ...