With the landmark discovery of the double-helical structure of DNA came the appreciation that the molecule’s two entwined strands are complementary — each serving as a template for the other during ...

As DNA strands ravel and unravel in an intricate dance, one notable event takes center stage: replication. This process is essential to life, but the finer details of its orchestrated steps are still ...

DNA replication is a complex process with many moving parts. In baker's yeast, the molecular complex Ctf18-RFC keeps parts of the replication machinery from falling off the DNA strand. Human cells use ...

Half a century ago, scientists Jim Watson and Alexey Olovnikov independently realized that there was a problem with how our DNA gets copied. A quirk of linear DNA replication dictated that telomeres ...

DNA replication is a tightly controlled process that copies the genetic code, allowing its instructions to be conveyed from one generation of cells to the next. In diseases like cancer, these ...